Research & Science Fairs · High school · US

Regeneron Science Talent Search

STS is widely regarded as the most prestigious pre-college research honor in the United States, running since 1942 with multiple Nobel laureates among its alumni. Because it is limited to seniors and accepts only independent individual research, the signal is exceptionally strong — even reaching the Top 300 Scholars is a decisive line on an application. For Irvine families the timing sits right around early applications, making it the moment when two or three years of research work finally converts into a credential.

Regeneron Science Talent Search
2026-27Latest season

Photo: Edward Jenner / Pexels

  1. Registration opensJun 12026
  2. Registration deadlineNov 52026
  3. Contest datesMar 11 – Mar 172027
  4. ResultsMar 162027

Verified from the official site on September 20, 2026 · www.societyforscience.org/regeneron-sts

Organizer
Society for Science (title sponsor: Regeneron Pharmaceuticals)
Eligibility
Open to students living in and attending their final year of secondary school (typically grade 12) in the US and its territories, regardless of citizenship; US citizens living abroad may also apply, but non-citizens attending American schools overseas are not eligible. The research must be independent, individual work — team research is not accepted, and splitting an experiment between two students still counts as team research. Work done alongside adult researchers at an institution is allowed, but the application must clearly delineate the student's independent contribution from the lab's collective work.
Format
Entirely online via the official portal at stsapply.societyforscience.org. The application includes essay questions, structured questions about the project, an original scientific paper of at most 20 pages, recommendations, transcripts and optional test scores. The 2027 window runs June 1, 2026 to November 5, 2026 at 8pm ET. Judging has two rounds: 300 Scholars are named from roughly 2,600 applicants (announced January 7, 2027), then 40 Finalists are selected (announced January 21, 2027). Finalists travel to Washington, DC for Finals Week, March 11–17, 2027, including a public exhibition on March 14 and the awards ceremony on March 16.
Contest dates
March 11 – 17, 2027
Fees
Neither the application instructions nor the FAQ page on the official site mentions an application fee. (No fee is stated officially; confirm on the application system pages.)
Awards
About $3.1 million is awarded annually. Each of the 300 Scholars receives $2,000, with another $2,000 going to their school. The 40 Finalists compete during Finals Week for more than $1.8 million, with a top prize of $250,000. Every finalist receives a guaranteed minimum award and spends the week in Washington, DC meeting leading scientists and program alumni.

About the competition

The Regeneron Science Talent Search, run by Society for Science, is the oldest and most prestigious pre-college science competition in the United States, operating since 1942 as a benchmark for young research talent. Applicants must live in and attend their final year of secondary school in the US or its territories, regardless of citizenship; US citizens abroad may also apply.

Unlike ISEF, STS requires strictly independent individual research — any team project is disqualified, and even two students splitting different stages of one experiment counts as team research. The application is fully online: an original paper of at most 20 pages, essay questions, structured questions about the research process, recommendations and transcripts, with test scores optional.

The 2027 cycle opened June 1, 2026 and closes November 5, 2026 at 8pm ET. About 2,600 students apply each year. Judges first name 300 Scholars (announced January 7, 2027; $2,000 each plus $2,000 to their schools), then select 40 Finalists (announced January 21, 2027).

Finalists attend Finals Week in Washington, DC from March 11–17, 2027, present publicly on March 14, and attend the awards ceremony on March 16, competing for more than $1.8 million with a top prize of $250,000. Judging looks past results to the originality of the question, methodological maturity, honest treatment of limitations, and the ability to explain the work clearly to non-specialists.

How to prepare

  • Have a complete, paper-ready dataset before the end of junior year. The November deadline overlaps early college applications, and leaving the write-up to October compromises both.
  • Independence is the easiest rule to violate. If you work in a university lab, confirm with your mentor in advance exactly which parts you designed and executed, and describe that boundary honestly and specifically in the application.
  • The essays are scored alongside the 20-page paper. Prepare three or four real moments where you got stuck, reconsidered and adjusted — concrete scenes separate applicants far better than general statements about loving science.

Frequently Asked Questions

Can an Irvine junior start preparing for Regeneron STS early?

Only students in their final year of secondary school, normally 12th grade, may apply, and juniors cannot submit. The application requires an original paper of up to 20 pages, and the research generally needs to be essentially finished by the summer before senior year, so 10th and 11th grade are the window for running experiments and collecting data, ideally scheduled around AP science coursework rather than against it.

Can international students apply to the Regeneron Science Talent Search?

Yes. Regeneron STS keys on residence and schooling rather than citizenship: a student who lives in the US or its territories and is attending their final year of secondary school there is eligible, including students on visas. US citizens living abroad may also apply; the one excluded group is non-citizens attending American schools overseas.

Can you submit a team project to Regeneron STS?

No. Regeneron STS accepts only independent, individual research, and team projects are ineligible — even two students dividing different parts of the same experiment counts as team research. This is one of the hardest differences from ISEF, which allows teams of up to three: a project done as a team cannot be repurposed for an STS application.

What's the difference between Regeneron STS and ISEF?

Three things differ. Eligibility: STS is seniors only, ISEF is open to grades 9-12. Format: STS is judged on an online application, a paper and essays, while ISEF requires winning an affiliated fair and then defending a poster in person. Teams: ISEF allows up to three students, STS is individual work only. A common approach is to use one body of research for both — fairs and ISEF in junior year, STS the following autumn.

What do you need to submit for Regeneron STS?

Everything is submitted online: essay responses, structured questions about the research project, an original paper of no more than 20 pages, teacher and mentor recommendations, a transcript, and optional test scores, which are not penalized if omitted. For 2027 the window ran June 1 to November 5, 2026 at 8pm ET, and recommendations were due by that same deadline.

Without a professor mentor or lab, can an Irvine student apply to Regeneron STS?

Yes. Society for Science states that neither a mentor nor an institutional lab is required, and it explicitly encourages at-home research; working with adult researchers at an institution is allowed, but the application must draw a clear line between the student's own contribution and the lab's collective work. When a school has no matching research program, a student can start with an independent project or sharpen research methods through an outside course such as EDUBUS. The real requirement is completed research with data and results.

How hard is Regeneron STS for an Irvine applicant, and does it help admissions?

Roughly 2,600 students apply each year. Three hundred are named Scholars, each receiving $2,000 with another $2,000 to their school, and 40 of those become Finalists who travel to Washington, DC for finals week and compete for over $1.8 million, with a top award of $250,000. That works out to just over a 10% chance of Scholar and under 2% of Finalist, and even reaching Scholar carries real weight in an application.

What grade should an Irvine student start preparing for Regeneron STS?

Work backwards from the early-November deadline of senior year: the paper and essays must be done by then, so the research itself needs to wrap up by the end of the summer before senior year. A steady sequence is settling on a direction in 10th grade, running experiments in 11th and taking them to a regional fair to sharpen the explanation, writing the paper that summer, and spending the fall of senior year on essays and recommendations — a rhythm that also keeps the work from colliding with the school year's exam calendar.

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