Research & Science Fairs · High school · INTL

Regeneron International Science and Engineering Fairwith the Orange County Science & Engineering Fair qualifying path

ISEF is the largest pre-college research competition in the world, and admissions readers treat it as hard evidence that a student can carry an independent research project end to end — far more weight than a school science fair. For Irvine families the path is unusually legible: place well at the local OCSEF, pass the selection interview, and your child represents Orange County internationally. That single credential strengthens essays, recommendation letters and demonstrated fit at once, which matters most for applicants targeting top STEM programs.

Regeneron International Science and Engineering Fair (with the Orange County Science & Engineering Fair qualifying path)
2026-27Latest season

Photo: RDNE Stock project / Pexels

  1. Registration opensSep 12026
  2. Registration deadlineFeb 12027
  3. Contest datesMar 12 – May 142027
  4. ResultsTBA

Verified from the official site on September 20, 2026 · www.societyforscience.org/isef

Organizer
Society for Science (the ISEF organizer); in Orange County the qualifying fair is run by the Orange County Science & Engineering Fair (OCSEF)
Eligibility
ISEF finalists must be in grades 9–12 (or equivalent) and must not have turned 20 on or before May 1 of the competition year. Each student may enter only one project; team projects are limited to three students. Continuous experimentation/data collection may not exceed 12 months and may not start before the officially specified month. Students must first win the right to advance at a Society-affiliated fair. For Irvine families that affiliated fair is OCSEF, which serves grades 6–12 at Orange County public and private schools; only grade 9–12 winners are eligible for the ISEF selection interviews.
Format
Students first register their project in the OCSEF online system (research plan plus safety/approval forms), clear the Scientific Review Committee, then upload an abstract and slide deck. In March they set up a physical board at Santa Ana College and are interviewed one-on-one by judges. OCSEF then holds invitation-only ISEF selection interviews. Those chosen represent Orange County at ISEF, where roughly 1,600 finalists from 60+ countries compete across 22 categories through poster displays, judge interviews and Grand Award Judging.
Contest dates
March 12 – 14, 2027 · May 8 – 14, 2027
Fees
The Society for Science website does not list a registration fee for ISEF finalists, and the 2027 season registration process published on the OCSEF website does not state an entry fee either. Travel and display-board costs for the regional fair are the family's responsibility. (No fee is stated officially; confirm on the registration system pages.)
Awards
ISEF distributes nearly $9 million. The top George D. Yancopoulos Innovator Award is $100,000; two Regeneron Young Scientist Awards are $75,000 each, plus several $50,000 and $10,000 prizes. Each of the 22 categories awards $6,000 / $2,400 / $1,200 / $600 for first through fourth place, and about 600 finalists receive special awards from corporate and university sponsors. At the OCSEF level, awards are given across 20 categories, and projects are selected to advance to the California Science & Engineering Fair, the Thermo Fisher Junior Innovators Challenge and ISEF.

About the competition

ISEF, run by the nonprofit Society for Science, is the top global research competition for students in grades 9–12. Roughly 1,600 finalists from more than 60 countries compete in 22 categories for close to $9 million in awards, scholarships and internships. The 2027 fair runs May 8–14 in Los Angeles, with Grand Award Judging on May 11–12.

There is no direct entry: the only way in is through a Society-affiliated regional fair. For Irvine students that fair is OCSEF, open to grades 6–12 in Orange County, holding its 72nd edition in the 2026-27 season.

OCSEF opens project registration and pre-approval on September 1, 2026; projects involving human participants, vertebrate animals, biohazards or hazardous chemicals must clear pre-approval by November 2, 2026; regular registration closes February 1, 2027; abstracts and slide decks are due February 22, 2027; setup, judging and the awards ceremony run March 12–14, 2027 at Santa Ana College.

OCSEF then holds invitation-only ISEF selection interviews for its strongest grade 9–12 projects. Judges weigh the significance of the question, methodological rigor, whether conclusions follow from the data, how well the student actually owns the work, and interview communication.

Key rules: one project per student per year, teams capped at three students from the same school and division, no more than 12 months of continuous experimentation, and safety forms approved before experimentation begins.

How to prepare

  • Work the calendar backwards: register as soon as it opens in September, and if your topic involves human participants, animals or biological materials, get pre-approval by November 2 — missing it ends the season, and it is the most common local disqualification.
  • Pick a narrow, testable question over an ambitious literature-review topic. Judges reward a project you can measure repeatedly within 12 months, with a control condition and raw data that genuinely supports the conclusion.
  • Keep a research log from day one, recording failed runs and why you changed course. OCSEF and ISEF interviews press on 'why did you do it this way,' and the log is the best proof the student, not a mentor, drove the work.

Frequently Asked Questions

How does an Irvine high schooler enter ISEF through OCSEF?

ISEF does not take individual entries; students must first win at a Society for Science affiliated fair. That fair is OCSEF, the Orange County Science & Engineering Fair, open to public and private school students countywide. The 2027 in-person fair runs March 12-14 at Santa Ana College, and advancing further requires an invitation to the ISEF selection interviews representing Orange County.

Where is ISEF 2027 being held?

Regeneron ISEF 2027 runs May 8-14 in Los Angeles, a drive rather than a flight for Orange County families, which cuts travel cost and makes it easier for parents to attend. The fair brings together more than 1,600 finalists from over 60 countries, competing across 22 categories.

What are the ISEF rules on how long you can work on a project?

Continuous experimentation and data collection may not exceed 12 months, and that period must fall within the 18 months before the fair. Last year's project can continue, but it must be declared as a continuation project, with Form 7 explaining how this year's question, method or scope differs from before — simply collecting more data under a new title does not qualify.

When do ISEF forms need to be signed — can you do them after the experiment?

No. ISEF works on approval-before-experimentation: Form 1 must be reviewed and signed by the Adult Sponsor before any work begins, and projects involving human participants, vertebrate animals or hazardous biological agents also need SRC or IRB approval in advance. Every signature date must precede the start of experimentation, and out-of-order dates are one of the most common reasons projects are disqualified.

Can an Irvine middle schooler compete in OCSEF or ISEF?

OCSEF is open to grades 6-12 in Orange County, so Irvine middle schoolers can compete for category awards and may advance to the California state fair or the Thermo Fisher Junior Innovators Challenge. ISEF itself only admits grades 9-12, under age 20 by May 1 of the competition year, so middle school is best used to build research method and presentation skills through OCSEF.

How many people can be on an ISEF team?

Three at most. Each student may submit only one project per year, and the team is judged as a single entry, so every member must be able to explain their own contribution — judges often question members separately. OCSEF adds its own rule: one application per project, with all members from the same school and grade division.

Can an Irvine student reach ISEF without a university lab?

Yes. Many of ISEF's 22 categories do not depend on expensive equipment — behavioral and social sciences, computational biology, mathematics and software, environmental engineering, materials testing. Judges reward a well-defined question, proper controls and sound analysis over an equipment list; when a school has no matching research club, a student can still start with an independent project or outside resources. Any project involving human participants, including a survey, needs IRB approval before data collection begins.

How much does an ISEF award help an Irvine student's UC application?

The total prize pool approaches $9 million, with each of the 22 categories awarding $6,000, $2,400, $1,200 and $600 for first through fourth place. Reaching ISEF through OCSEF is already treated as strong evidence of research ability in University of California applications, and a category award adds further weight.

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